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Clomiphene Citrate (Oral)

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Clomiphene Citrate (Oral)

Posted on 02 September 2010 by admin

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Proprietary names:

Clomid

Average dose:

Men: 50-100 mg/day

Description

Clomid is the commonly referenced brand name for the drug clomiphene citrate. It is not an anabolic steroid, but a prescription drug generally prescribed to women as a fertility aid. This is due to the fact that clomiphene citrate shows a pronounced ability to stimulate ovulation. This is accomplished by blocking/minimizing the effects of estrogen in the body. To be more specific Clomid is chemically a synthetic estrogen with both agonist/antagonist properties, and is very similar in structure and action to Nolvadex. In certain target tissues it can block the ability of estrogen to bind with its corresponding receptor. Its clinical use is therefore to oppose the negative feedback of estrogens on the hypothalamic-pituitary-ovarian axis, which enhances the release of LH and FSH. This of course can help to induce ovulation.

For athletic purposes, Clomid does not offer a tremendous benefit to women. In men however, the elevation in both follicle stimulating hormone and (primarily) luteinizing hormone will cause natural testosterone production to increase. This effect is especially beneficial to the athlete at the conclusion of a steroid cycle when endogenous testosterone levels are depressed. If endogenous testosterone levels are not brought beck to normal, a dramatic loss in size and strength is likely to occur once the anabolics have been removed. This is due to the fact that without testosterone (or other androgens), the catabolic hormone cortisol becomes the dominant force affecting muscle protein synthesis (quickly bringing about a catabolic metabolism). Often referred to as the post-steroid crash, it can quickly eat up much of your newly acquired muscle. Clomid can play a crucial role in preventing this crash in athletic performance. As for women, the only real use for Clomid is the possible management of endogenous estrogen levels near contest time. This can increase fat loss and muscularity, particularly in female trouble areas such as this hips and thighs. Clomid however often produces troubling side effects in women (discussed below), and is likewise not in very high demand among this group of athletes.

Male users generally find that a daily intake of 50-100 mg (1-2 tablets) over a four to six week period will bring testosterone production back to an acceptable level. A very common regime of dosing is; 300 md/day 1, 100 mg/day for days 2-11, and 50 mg/day for days 12-21. This raise in testosterone should occur slowly but evenly throughout the period of intake. Since an immediate boost in testosterone is often desirable, many prefer to combine Clomid with HCG (Human Chorionic Gonadotropin) for the first week or two after the steroids have been removed. The kick-start from HCG also helps to restore the normal ability for the testes to respond to endogenous LH, which may be hindered for some time after the cycle is ended due to a prolonged state of inactivity. Once the HCG is stopped, the user continues treatment with Clomid alone. HCG should not be used for longer than two or three weeks though, as the resulting increased testosterone and estrogen levels may again initiate negative feedback inhibition at the hypothalamus. When planning your ancillary drug program, it is also important to remember that injectable steroids can stay active for a long duration. Using ancillary drugs the first week after a long acting injectable like Sustanon has been stopped may prove to be wholly ineffective. Instead, the athlete should wait for two to three weeks, to a point where androgen levels will be diminishing. Here the body will be primed and ready to restore testosterone production.

Clomid and HCG are also occasionally used periodically during a steroid cycle, in an effort to prevent natural testosterone levels from diminishing. In many instances this practice can prove difficult however, especially when using strong androgens for longer periods of time. There is also no exact method for using the two drugs in this manner. Some have experimented by periodically administering small doses of HCG along with one or two tablets of Clomid, perhaps for a few days at a stretch followed by a longer break. An on/off schedule would be implemented; for fear that this combination may lose some effectiveness if used continuously for this purpose. This method of intake may prove to be effective, although it is really much more feasible to stimulate testosterone production after the cycle than to try and maintain it for the long duration during.

In addition to helping with the post-cycle testosterone crash, this drug can also help with elevated estrogen levels during a steroid cycle. A high estrogen bevel puts an athlete in serious risk of developing gynecomastia, which is an obvious unwanted side effect. With the intake of Clomid, the athlete can hopefully reduce his risk for developing gynecomastia. The estrogen “blocking” properties of Clomid appear to be slightly weaker than Nolvadex in comparison however, which is why it is not usually thought of as an equal substitute for estrogen maintenance. Of course both drugs have similar actions in the body. and are relatively interchangeable for this purpose. Clomid can likewise also be used as a maintenance anti-estrogen throughout the duration of steroid cycle with good confidence, just as is done with Nolvadex. In most instances this will prove equally sufficient, the drug effectively minimizing the activity of estrogen in the body and warding off gyno and excess water/fat retention. Unfortunately just as with Nolvadex this is not always the case however, and many find it necessary to addition another anti-estrogenic drug. The most common adjunct is Proviron, an oral DHT used to competitively lower aromatase activity and raise the androgen to estrogen ratio. The Clomid/Nolvadex and Proviron combination is extremely effective, although we could alternately replace them both with a more specific aromatase inhibitor such as Arimidex,Femara, or Aromasin. While stronger at combating estrogen in most cases, these drugs are also typically much more costly.

As for toxicity and side effects, Clomid is considered a very safe drug. Bodybuilders seldom report any problems, but listed possible side effects do include hot flashes, nausea, dizziness, headaches and temporarily blurred vision. Such side effects usually only appear in females however, as they feel the effects of estrogen manipulation much more readily than men. While female athletes can clearly gain some benefit from this substance, estrogen manipulation is probably not the most comfortable way to go about cutting up. Should it still be used for such purposed and side effects do become pronounced, the drug of course is to be discontinued and (at least) a break taken from it.

Clomiphene citrate is widely available on the black market in a variety of brand names as well as generic tabs and liquid versions.



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Drostanolone Propionate (Injectable)

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Drostanolone Propionate (Injectable)

Posted on 02 September 2010 by admin

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Proprietary names:

Masteron

Therapeutic dose:

Men: 300-500 mg/week

Description

Masteron is an injectable preparation containing the steroid drostanolone propionate. Drostanolone is a derivative of dihydrotestosterone, most specifically 2alpha-methyldihydrotestosterone. As a result, the structure of this steroid is that of a moderate anabolic/potent androgen which does not aromatize to estrogen. Water retention and gynecomastia therefore do not come into play with this drug. Masteron may in fact exhibit anti-estrogenic activity in the body, competing with other substrates for binding to aromatase. This would reduce the conversion rate of other steroids, Masteron acting in the same way as the oral steroid Proviron.

Bodybuilders have a strong like for non-aromatizing androgens, and find Masteron very useful in a cutting phase. It is generally used for a number of weeks prior to a competition, in an effort to bring out an improved look of density and hardness to the muscles. As long as body fat percentage is low enough, Masteron should work very well. Provided everything fits as if should, the user can achieve that “ripped” look so popular to professional bodybuilding. The androgenic effect can also be crucial during this period, a time when caloric intake is drastically lowered. The user is provided added “kick” or “drive” to push through the grueling training sessions leading up to the show. Recreational users might also be interested in Masteron. Although dihydrotestosterone is not highly active in muscle tissue, the 2 alkylation present on drostanolone considerably intensifies its anabolic effect. It can therefore be used somewhat effectively as bulking agent, providing a consistent gain of high quality muscle mass. It can also be successfully combined with other steroids for an enhanced effect. Mixing drostanolone with an injectable anabolic such as Deca-Durabolin or Equipoise can prove quite useful for example, the two providing notably enhanced muscle gain without excessive water retention. For greater mass gains, a stronger androgen such as Dianabol or an injectable testosterone would do the trick. The result here can be an extreme muscle gain, with a lower level of water retention & other estrogenic side effects than if these steroids were used alone (usually in higher doses). Masteron could of course be used during cutting phases of training as well. A cycle of this drug combined with Winstrol, Primobolan or Oxandrolone should provide great muscle retention and fat loss, during a period which can be very catabolic without steroids. It is an added benefit that none of these steroids aromatize, and therefore there is no additional worry of unwanted water and fat retention.

Since the propionate ester is used with this compound, injections need to be repeated at least every 3 or 4 days in order to maintain a consistent level of hormone in the blood. The weekly dosage is in the range of 300-500mg.

Since estrogen is not an issue, side effects are generally mild with this steroid. As discussed earlier, gynecomastia, water retention, and high blood pressureare not a problem. Masteron is also not liver toxic, so there is little concern stress will be placed on this organ, even during longer cycles. The only real side effects would be from the basic androgenic properties of dihydrotestosterone. These includes oily skin, acne, body/facial hair growth, aggression and accelerated hair loss. Since this compound is already a synthetic DHT, Proscar would have no impact on the level of androgenic effects. Men with a receding hairline or those with a predisposition for baldness may therefore wish to stay away from Masteron completely, as the potent androgenic effect of this steroid can easily accelerate this condition.



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Testosterone Suspension (Injectable)

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Testosterone Suspension (Injectable)

Posted on 02 September 2010 by admin

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Therapeutic dose:

Men: 50-200 mg/day

Description

Testosterone suspension is an injectable preparation containing testosterone (no ester) in a water base. Since testosterone is not highly water soluble, the steroid will noticeably separate from the solution when the vial is left to sit. A quick shake will put the drug back into suspension, at least temporarily, so that it can be withdrawn in a consistent dosage. Although it may contain testosterone without the benefit of an ester, and contrary to popular belief, the microcrystal design of this injectable will sustain an elevated testosterone release for 2-3 days. Clearly the suspension we see today is not the basic water plus testosterone design used in the 1940′s. And since the drug will not leave circulation in a matter of hours, it is obviously useful.

Among bodybuilders, “suspension” is known to be an extremely potent mass agent. It is often ranked as the most powerful injectable steroid available, resulting in an incredibly rapid gain of muscle mass and strength. This is largely due to the very fast action of this drug, as the water-based steroid will begin to enter the blood stream almost immediately after an injection is given. Unlike longer esters such as enanthate or cypionate which take weeks for blood levels to reach maximiun theraputic levels, with suspension it is just a matter of days. Clearly the anabolic effect of this testosterone will be realized much more quickly than we would expect with an oil based (esterified) preparation.

It is also important to remember that 100mg of a testosterone ester is not equivalent to 100mg testosterone of pure testosterone (as in suspension). When an ester is present, its weight is obviously included in the preparation’s milligram total. Looking at Testosterone enanthate, 100mg of this compound equates to only 72mg of raw testosterone. So the bodybuilder who uses 400mg of enanthate weekly is really getting about 288mg of testosterone into his body each week. This is clearly a great increase over the endogenous testosterone level of the average male, which is in the range of 2.5 to 11 mg per day. But the general point is that during a cycle of Testosterone suspension we will often see a much more dramatic intake of testosterone on average than is typically utilized with oils. Following common advice, the athlete will commonly inject a full 100mg of testosterone daily, a total of 700 milligrams per week. This is up to 40 times the amount produced by a normal male. Those who have attempted such a cycle are rarely disappointed with the results, as such heavy doses of this hormone will produce nothing less than a dramatic weight gain.

The most popular practice with Testosterone suspension is to inject the drug every day. The dosage will vary greatly depending on the needs of the individual, but is most often in the range of 50mg to 100mg per shot. In most cases the results will be amazing. Although some users will complain about discomfort when injecting water-based steroids, suspension is usually well tolerated.

As would be expected with a strong androgen, suspension can produce a number of unpleasant side effects. As with any testosterone product there will be a high rate of estrogen conversion. Estrogen levels in fact build very quickly with Testosterone suspension, which is probably the worst testosterone to use when wishing to avoid water bloat. Gynecomastia can also develop very quickly during a cycle, and in many cases this drug will be intolerable without additionally taking an anti-estrogen. A combination of Nolvadex and Proviron is an effective way to avoid experiencing such side effects, and is often taken from the onset of a cycle in order to prevent such occurrences before they become a problem. Sensitive individuals may find an investment in the anti-aromatase Arimidex, Femara, or Aromasin to be wiser. These anti-aromatase drugs are much more effective at controlling estrogen. It is also important that the athlete monitor blood pressure and kidney functions closely during a heavy cycle, as water retention becomes more pronounced. Although testosterone puts very little strain on the liver, this drug can be harsh to the kidneys at higher dosages. Of course if the athlete is encountering noticeably high blood pressure or trouble urinating (pain or darkening of the urine), the cycle should probably be discontinued and the doctor paid a visit. Since it converts to DHT. one can therefore expect to endure oily skin, acne, increased aggression and body/facial hair growth during a typical cycle. Propecia/Proscar would be a good idea for those predisposed to male pattern baldness, as suspension is known to aggravate this condition quite easily. Men with an existing hair loss problem may actually prefer to stay far away from this steroid altogether, finding it to be just to strong an item to take risks with. The slower acting oil based injectables like enanthate or cypionate would be a much better place to start with if one still desires to use an injectable testosterone.

Endogenous testosterone production will be quickly and efficiently reduced when using suspension. This can often reach the point of severe testicular shrinkage (atrophy). Some athletes will periodically take HCG while on a cycle, in order to keep this effect to a minimum. Even if no such drug is used during, a combination of HCG and Clornid/Nolvadex should always be used as the cycle is discontinued.

Overall, suspension is an extremely powerful drug, but also one that is prone to causing many side effects. Those looking for only a potent mass agent need not look no further, Suspension will certainly get the job done.



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Trenbolone Acetate (Injectable)

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Trenbolone Acetate (Injectable)

Posted on 02 September 2010 by admin

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Therapeutic dose:

Men: 75 mg every day or two days

Description

Trenbolone is a very potent androgen with strong anabolic activity. It is well suited for the rapid  buildup of strength and muscle mass, usually providing the user exceptional results in a relatively short time period. The anabolic effect of this drug is often compared to popular bulking agents such as  testosterone or Dianabol, with one very important difference. Trenbolone does not convert to estrogen.

This is indeed a very unique compound since mass drugs, almost as a rule, will aromatize (or cause  other estrogen related troubles) heavily. When we think of taking milder (regarding estrogen) steroids we usually expect much weaker muscle growth, but not so with Trenbolone. Here we do not have to worry about estrogen related side effects, yet still have an extremely potent mass/strength drug. There is no noticeable water retention, so the mass gained during a cycle of Trenbolone will be very hard and defined (providing fat levels are low enough). Gynecomastia is also not much of a concern, so there shouldn’t be any need to addition an anti-estrogen if trenbolone is the only steroid administered.

The high androgen level resulting from this steroid, in the absence is excess estrogen, can also  accelerate the burning of body fat. The result should be a much tighter physique, hopefully without the need for extreme dieting. Trenbolone can therefore help bring about an incredibly hard, ripped physique and is an ideal product for competitive bodybuilders.

Trenbolone is notably more potent than testosterone, and has an effect that is as much as three times as strong on a milligram for milligram basis. Likewise we can expect to see some level of androgenic side effects with use of this compound. Oily skin, aggressive behavior, acne and hair loss are therefore not uncommon during a cycle with this steroid. The androgenic nature of this drug of course makes it a very risky item for women to use, the chance for virilization symptoms extremely high with such a potent androgen.

Trenbolone is also much more potent than testosterone at suppressing endogenous androgen production. This makes clear the fact that estrogen is not the only culprit with negative feedback inhibition, as here there is no buildup of this hormone to report here. There is however some activity as a progestin inherent in this compound, as trenbolone is a 19-nortestosterone (nandrolone) derivative (a trait characteristic of these compounds). However it seems likely that much of its suppressive nature still stems from its powerful androgen action. With the strong impact trenbolone has on endogenous testosterone, of course the use of a stimulating drug such as HCG and/or Clomid/Nolvadex is recommended when concluding steroid therapy (a combination is preferred). Without their use it may take a prolonged period of time for the hormonal balance to resume, as the testes may at first not be able to normally respond to the resumed output of endogenous gonadotropins due to an atrophied state.

Those who have used Trenbolone regularly would often claim it to be indispensable. A daily dosage of 37.5-75 mg is the most popular range when running a cycle. While Trenbolone is quite potent when used alone, it was generally combined with other steroids for an even greater effect. During a cutting phase one could add a non-aromatizing anabolic such as Winstrol or Primobolan. Such combinations will elicit a greater level density and hardness to the muscle. One could also bulk with this drug, with the addition of stronger compounds like Dianabol or Testosterone. While the mass gain would be quite formidable with such a stack, some level of water retention would probably also accompany it. Moderately effective anabolics such Deca-Durabolin or Equipoise would be somewhat of a halfway point, providing extra strength and mass but without the same level of water bloat we see with more readily aromatized steroids.



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