After a steroid user has finished a cycle his natural production of hormones particularly testosterone is suppressed and needs to be restore to its original state quickly to minimise some of the post cycle side effects such as
depression and loss in strength and weight. Post cycle therapy is an after cycle drug regime which is designed to do this and is in my opinion more important from the cycle itself. I would rather be moderately big and my balls still work then look like the hulk and have pea sized nuts.
The 2 main drugs used for PCT are Tamoxifen (nolvadex) and Clomid. There are others but these two are considered to be the best.
Clomid and Nolvadex are both anti-estrogens belonging to the same group of triphenylethylene compounds. They are structurally related and specifically classified as selective estrogen receptor modulators (SERMs) with mixed agonistic and antagonistic properties. This means that in certain tissues they can block the effects of estrogen, by altering the binding capacity of the receptor, while in others they can act as actual estrogens, activating the receptor.
In men, both of these drugs act as anti-estrogens in their capacity to oppose the negative feedback of estrogens on the hypothalamus and stimulate the heightened release of GnRH(Gonadotropin Releasing Hormone). LH output by the pituitary will be increased as a result, which in turn can increase the level of testosterone by the testes.
Both drugs do this, but for some reason bodybuilders persist in thinking that Clomid is the only drug good at stimulating testosterone. What you will find with a little investigation however is that not only is Nolvadex useful for the same purpose, it should actually be the preferred agent of the two.
IMPORTANT: Before attempting any cycle understand all compound uses and reasons behind them. Use at your own risk.
